Alpha Lipoic Acid Side Effects Thyroid

Take Your Medication Correctly

What Are the Most Common Alpha Lipoic Acid Side Effects

In order for it to do its job, you have to follow the directions. That includes when, how, and how much. If you take insulin, store it at the right temperature, out of sunlight. Let your doctor know if your blood sugar often measures too high or too low. Your dose, or the kind of medicine you take, may need to be adjusted.

Ala For Thyroid Health

Many studies on relation of ALA to thyroid health have been done the results of which indicate that ALA can avoid or treat dysfunction of thyroid gland and the complications resulting from thyroid conditions.

Protection for cancer patients: Exposure to radiation therapy in cancer patients can result in hypothyroidism. Animal studies done pre-clinically indicate ALA can safeguard the gland from ill effects of radiation. ALA due to its anti-oxidant effect can exert anti-cancer effect on the cell lines of cancerous thyroid cells.

Action on subclinical hypothyroidism: A research study on subclinical hypothyroidism published in PubMed in 2010 indicates that ALA enhances endothelial function. This is brought about by reduction in number of free radicals resulting in better arterial flow.

The use of ALA does not however change the levels of thyroid hormone. If the endothelial dysfunction is not treated it can result in atherosclerosis. This is especially true in case of Hashimotoâs Thyroiditis.

Influence on thyroid hormone secretion: ALA can influence T4 to T3 conversion according to a 1991 study. This is the reason patients need to be careful when taking thyroid hormones such as levothyroxine and alpha lipoic acid simultaneously.

There should be a minimum duration of 4 hours between the two medications for the ALA to be safe. The study indicates that nearly 56% suppression of T4 conversion occurred when ALA and levothyroxine were taken simultaneously.

Promotes Normal Cardiovascular Function

Blood vessels are lined with a single layer of cells called the endothelium. Healthy endothelial cells help to relax blood vessels. The endothelial lining can become compromised due to illnesses, leading to poor vascular health. As we age, oxidative stress negatively affects cardiovascular health. Unchecked, oxidative stress will damage endothelial tissue in arteries and affect blood flow, including to the heart. While the degradation of heart function can lead to serious health issues, antioxidants help promote a healthy heart and cardiovascular system.

One study revealed that when ALA was introduced to previously damaged blood vessel cells in vitro , it promoted normal function of the cells and supported the cells antioxidant defenses. In another study, IV-administered alpha-lipoic acid helped promote normal circulation. Overall, ALA has a cardioprotective effect which may be helpful to people seeking to support their heart.

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What Should I Watch Out For

Do not use alpha-lipoic acid if you have:

Thiamine deficiency
Thyroid disease

If you have HIV, tell your healthcare provider you are taking alpha-lipoic acid. This remedy may affect your blood tests.

If you have diabetes: This remedy may affect your blood sugar level and change the amount of insulin or other diabetes medicines you may need. Talk to your healthcare provider about this.

If you need emergency care, surgery, or dental work, tell the healthcare provider or dentist you are taking this remedy.

Talk to your healthcare provider or pharmacist about any natural remedy that you are using or thinking about using. If your provider does not tell you how to take it, follow the directions that come with the package. Do not take more or take it longer than recommended. Ask about anything you do not understand. Remember:

Natural remedies are not always safe.
You should not take them if you are pregnant or breast-feeding without your healthcare providers approval. They should not be taken by infants, children, or older adults without your providers approval.
They affect your body and may interact with prescription medicines that you take.
Natural remedies are not standardized. They may be contaminated. They may also have different strengths and effects.

All Information About Does Alpha Lipoic Acid Interfere With Thyroid Medication

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Alpha Lipoic Acid And Heart Palpitations

Why do some people experience heart palpitations while taking alpha-lipoic acid? Medication interactions are to blame in most cases. As mentioned previously, ALA can affect thyroid hormone medications such as Synthroid. Excess ALA levels can lower thyroid hormone levels, interfering with normal heart rhythms.

Is Alpha Lipoic Acid Really Safe

by Heidi | Nov 3, 2022 | Skincare Health Tips |

There are a few reports of skin rashes associated with the use of alpha lipoic acid supplements. However, it is not clear if the alpha lipoic acid is the cause of the rash or if it is due to another factor. If you are considering taking alpha lipoic acid, it is important to speak with your healthcare provider first to discuss the potential risks and benefits.

Glutathione is an organic compound found in every cell of the body that functions as a mitochondria. The antioxidant properties of ALA have been linked to a number of health benefits. In a few studies, some promising results have been discovered with ALA for skin health. Most people appear to be safe when taking ALA supplements orally or topically, and side effects are generally mild when taken at the recommended dose. ALA has the potential to have anti-aging effects due to its antioxidant properties, which protect against sun damage and stress caused by pollution and other environmental factors. A topical application of ALA, as well as a supplement, can be taken orally or in a gel or cream. The research has found that doses of up to 1,800 mg have no serious side effects, but long-term effects have been less studied.

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Alpha Lipoic Acid For Weight Loss

While it might not have a significant impact on weight loss, alpha lipoic acid helps in a more round-about way. In various studies, some people who took the supplement lost an average of 1.5 pounds more than those taking a placebo over 14 weeks.

An additional study showed that over 23 weeks, people who took alpha lipoic acid lost 2.78 pounds more than the placebo group. Over five months, 3 lb is not a significant amount, but weight loss is an added benefit to all the other good things this does in the body.

The primary mechanism for weight loss is the suppression of the AMP-activated protein kinase. The more activated AMPk there is, the hungrier you feel. So, when alpha lipoic acid helps suppress this activity, you’re less hungry and when you arent hungry, you make better choices.

Alpha Lipoic Acid For Weight Loss And Thyroid Health

Alpha Lipoic Acid400 30 Capsules

People are always looking for ways to lose weight as quickly and efficient as possible.

Even with a load of options on the table in todays market, losing weight is still harder than it looks. Most people use shakes, food plans, and supplements to help lose weight, but people should consider a different option which is called alpha lipoic acid or ALA.

Now, many people have never heard about alpha lipoic acid, but it should be considered a great weight loss option for people who are overweight and obese.

Do not be concerned about the word acid because many fruits have acids within them that help regulate the body, and alpha lipoic acid is no different in that sense.

Effect On Weight Loss

For people who are overweight or obese, ALA can help in reducing the weight to some extent.

A study done on its effect on weight gain shows that ALA has the potential to cause a significant amount of weight loss albeit the change being small and of short term.

Another research study on the effect of ALA on weight loss indicated that a mild loss of weight occurred which makes it a good supplement to consider for weight loss. The anti-inflammatory and anti-oxidant effect also provides distinctive advantage.

The anti-inflammatory effect is of significance in thyroid eye disease.

What Products Might Interact With This Remedy

When you take this remedy with other medicines, it can change the way the remedy or the medicines work. Vitamins and certain foods may also interact. Using these products together might cause harmful side effects. Before taking this remedy, talk to your healthcare provider if you are taking:

Diabetes medicines such as glipizide , glyburide , insulin, metformin , pioglitazone , repaglinide , and rosiglitazone
Medicines used to treat cancer such as cisplatin, doxorubicin , hydroxyurea , vinblastine, and vincristine
Natural remedies such as ephedra, ginger, gotu kola, stinging nettle, devils claw, fenugreek, garlic, guar gum, horse chestnut, ginseng, and psyllium
Thyroid medicines such as levothyroxine , liothyronine , liotrix , and thyroid

Do NOT drink alcohol while taking this remedy unless your healthcare provider approves.

If you are not sure if your medicines might interact, ask your pharmacist or healthcare provider. Keep a list of all your medicines with you. List all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take. Be sure that you tell all healthcare providers who treat you about all the products you are taking.

Keep all natural remedies and medicines out of the reach of children.

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Nutritional & Therapeutic Supplements

If your body doesn’t produce enough ALA or you don’t get enough in your diet, which is especially true in Western culture where people consume processed foods and are exposed to environmental toxins, a nutritional supplement that contains ALA can help. Supplemental servings of ALA typically range from 50 to 600 mg, which is up to 1000 times more than naturally occurs in food. Most supplements contain 50-50 combinations of the mirror image isomers, while the highest quality supplements only contain pure R-LA. Studies show that the body absorbs ALA best on an empty stomach.

Special Precautions & Warnings

Pregnancy and breast-feeding

Diabetes: Alpha-lipoic acid can decrease blood sugar levels. Your diabetes medications might need to be adjusted by your healthcare provider.

Excessive use of alcohol/thiamine deficiency: Alcohol can lower the amount of thiamine in the body. Taking alpha-lipoic acid when there is a shortage of thiamine might cause serious health problems. If you drink a lot of alcohol and take alpha-lipoic acid too, you should take a thiamine supplement.

Thyroid disease: Taking alpha-lipoic acid might interfere with treatments for under-active or over-active thyroid.

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What Is This Product Used For

Alpha-lipoic acid is also called ALA. It is used to help relieve some types of nerve pain caused by diabetes or certain drugs. It may also help stop cell damage in the body. It may help lower the pain in burning mouth syndrome. ALA has also been used for macular degeneration, an eye problem that occurs with age or diabetes.

Alpha Lipoic Acid Side Effects

Alpha Lipoic Acid is an antioxidant and a nutritional supplement which is used by many people since 1950s for different purposes. Although beneficial for the health, it may have some side effects. This article provides information regarding the same.

Alpha lipoic acid is found naturally in various food items like vegetables and meats. It is required by our body for proper functioning. This antioxidant is fat soluble and water soluble, and thus, neutralizes the damage caused by the free radicals. It dissolves the toxic substances in liver by increasing the production of glutathione. It enhances the bodys sensitivity to insulin. It reduces the fats, and thus, makes the body lean. It also helps in the detoxification of the liver. This antioxidant can also treat medical conditions like glaucoma and hyperglycemia. Most of the time, ALA does not cause any kind of side effects however, in a few cases, when consumed in excess or if a person is allergic to it, then there can be severe side effects on the body. An adult can safely consume 300 mg to 600 mg of alpha lipoic acid per day.

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About Generic Versions Of Levothyroxine:

The reason why it’s particularly important to consider possible supplement interactions when taking thyroid medication is that it has a “narrow therapeutic index.” This means that drug levels must be maintained within a relatively narrow range to be effective and not cause side effects. For this same reason, switching from a branded thyroid medication to a generic, or from one generic to another, can be problematic if the two drugs are not closely bioequivalent or are formulated differently — causing one to release its active ingredient at a different rate than the other under certain circumstances, such as when taken with food or without food.

The Neuroprotective Effect Of

Everything Neuropathy: Alpha Lipoic Acid

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What Are The Precautions When Taking This Product

Always check with your doctor before you use a natural product. Some products may not mix well with drugs or other natural products.
This product may interfere with some lab tests. Be sure to talk with your doctor about this and all drugs you are taking.
Be sure to tell your doctor if you are pregnant, plan on getting pregnant, or are breastfeeding. You will need to talk about the benefits and risks of using this natural product.
If you have blood sugar problems, keep hard candies, glucose tablets, liquid glucose, or juice on hand for low blood sugar.
Take extra care and check with your doctor if you have:
Thyroid problems

What Happens If I Take Too Much Alpha

Since ALA is not an essential nutrient, there is no recommended amount to get in your diet or through supplements. There also is no set upper intake limit. If you take too much ALA, you may experience some of the side effects discussed above, but they tend to resolve when the supplement is stopped.

Otherwise, one reported case of a 70-year-old woman who experienced multiple organ failures from too much ALA. But this was partially caused by a prescribing error. Accidental exposure to ALA caused one toddler to experience convulsions. In general, it is important to keep all medications and supplements out of the reach of children and pets to avoid accidental ingestion.

Additionally, a 22-year-old woman was admitted to an emergency department after an intentional overdose of ALA. She presented with tachycardia or a rapid heartbeat, altered mental state, metabolic acidosis, and an abnormal electrocardiogram . She was treated and discharged from the hospital three days later.

In nonhuman animal studies, high levels of ALA were reported to cause changes in liver function, alteration in liver enzymes, apathy, and confusion. While we canât conclude toxicity using nonhuman animal studies alone, it may be worth considering when frequently taking high doses of ALA.

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Managing Autoimmune Thyroid Disease

Autoimmune thyroid diseases , including Graves disease and Hashimotos thyroiditis are the most common form of thyroid dysfunction, with HT being the most frequent. In HT and GD the immunological mechanisms involved are closely related, while the phenotypes probably differ because of the specific type of immunological response that occurs.

Promotes A Strong Brain & Sharp Memory

As you get older, your body produces less alpha-lipoic acid, which means you have less protection from free radicals than when you’re young. Some research shows that people living in heavily polluted cities experience cognitive damage due to higher-than-normal levels of environmental toxins.

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Alternative Treatment Supplements And Hashimotos Disease Diet

Natural extracts containing thyroid hormone such as desiccated thyroid extract. Even though most healthcare providers suggest synthetic thyroxine, natural extracts containing thyroid hormone derived from the thyroid glands of pigs are also available. These products such as for example Armour Thyroid contain both levothyroxine and triiodothyronine . However, these extracts are available by prescription only, so do not confuse these with the glandular concentrates sold in natural foods stores. Moreover, doctors have a number of concerns about such thyroid hormone extracts such as Armour Thyroid, including:
The T-4 and T-3 balance is not the same in animals as it is in humans.
The exact amount of T-4 and T-3 in each batch of a natural extract product can vary, leading to unpredictable levels of these hormones in your blood .

non iodized salt

vegetables , vegetable oils and fruits

drinks such as tea, black coffee, soda, lemonade, fruit juices, beer and wine

herbs and spices

honey, sugar, jam, and jelly

unsalted nuts and nut butter

in addition, beef, chicken, turkey, veal, and lamb .

Compiled by Maria-Helena Loik

Antioxidant Selenium And Alpha Lipoic Acid

Not only is selenium essential for normal thyroid function via its contribution to the deiodination enzymes involved in converting T4 to the active thyroid hormone T3, low selenium concentrations have been found to cause autoimmune processes in the thyroid gland. As a result research has been conducted on the effectiveness of selenium for the management and progression of AITD .

In a pilot study on GD patients, selenium therapy used concurrently with routine methimazole treatment inhibitor) was compared to methimazole alone for 6 months. The addition of selenium was found to assist in achieving better outcomes for patients. Selenium supplementation achieved greater decreases in free T4 and T3, greater increases in TSH and significantly lower anti-TSH-receptor antibodies . There was also a higher rate of remission in the selenium group compared to controls, and a higher percentage of patients achieved normal TRAb within the 6 month treatment period.

A common symptom of GD is ophthalmopathy/orbitopathy . This is suggested to be the result of greater levels of inflammation and oxidative stress which contribute to adipose tissue expansion behind the eyes, linked to the action of inflammatory cytokines which activate orbital fibroblast secretion of glycosaminoglycans, inducing orbital fibrosis and oedema.

Selenium has demonstrated its therapeutic potential as an agent for Graves’ orbitopathy.

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