Wednesday, February 28, 2024

How To Treatment Thyroid Gland

Natural Remedies For Thyroid Health

How To Boost Your Thyroid Gland : Thyroid Treatment – VitaLife Show Episode 105

By Dr. Josh Axe, DC, DNM, CN

What Im going to share with you today are natural remedies for thyroid health. There are more people than ever before that are struggling with hypothyroidism, Hashimotos disease, hyperthyroidism and Graves disease.

If you personally are one of those people who has a sluggish thyroid, a slow metabolism, maybe you exercise and the weight doesnt come off like it should, you struggle with adrenal fatigue or lack of energy all of those are warning signs that you might have a thyroid issue.

Im going to cover my top five natural remedies that are safe, healthy and effective for improving your thyroid function and helping your body heal any sort of thyroid issue.

Conditions Affecting Thyroid Hormone Replacement Requirements

Because thyroid hormone is highly protein bound, medical conditions that alter the amount of binding hormones and drugs that compete for binding may change the amount of available free thyroid hormone. The thyroid replacement dosage must be changed in response to alterations in binding status.

With conditions that cause an increase in serum binding proteins, such as high estrogen states , oral contraceptive use or postmenopausal estrogen replacement, the dosage of levothyroxine must be increased. In contrast, androgens decrease levels of thyroid binding proteins, necessitating a reduction in the dosage. Older patients also have lower serum protein levels and may require reductions in their maintenance dosage over time. Nephrosis, protein-losing enteropathies and cirrhosis are other conditions that require a reduced thyroid hormone dosage.

A number of medications reduce the absorption of thyroid hormone from the intestines, necessitating an increase in the replacement dosage .21 Other drugs accelerate the metabolism of thyroid hormone, and an increase in the replacement dosage is then required. When these medications are started or adjusted, the TSH value should be monitored to determine whether additional thyroid hormone replacement is indicated.

Fast Facts On Hypothyroidism

Hypothyroidism develops slowly. Symptoms may go unnoticed for a long time, and they may be vague and general.

Symptoms vary a great deal between individuals, and they are shared by other conditions. The only way to obtain a concrete diagnosis is through a blood test.

Treatment for hypothyroidism focuses on supplementing the thyroid hormone. At present, doctors cannot cure hypothyroidism but they can help people to control it in most cases.

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How Is The Dose Of Thyroid Hormone Chosen

When you are first started on thyroid hormone, the initial dose is carefully selected based on information such as your weight, age, and other medical conditions. The dose may need to be adjusted periodically by your physician to keep the thyroid levels normal. Your physician will make sure the thyroid hormone dose is correct by performing periodic physical examination and checking TSH levels.

There are several brand names of thyroid hormone available. Although these all contain the same levothyroxine , there are different inactive ingredients in each of the brands. In general, it is best for you to stay on the same brand, or the same manufacturer of a generic for consistency. If a change in brand or manufacturer is unavoidable, you should make your physician aware of the change, so that your thyroid hormone levels can be rechecked. If your pharmacy or insurance plan changes your thyroid hormone to a generic preparation, it is important for you to inform your physician.

Who Needs Thyroid Hormone Replacement Therapy

How to Heal Your Thyroid Naturally!

Thyroid hormone therapy is generally prescribed when your thyroid is not making enough thyroid hormone naturally. This is a condition referred to as hypothyroidism. Other reasons for using thyroid hormone therapy may rarely include:

  • To control the growth of the enlarged thyroid gland

  • To control the growth of nodules on the thyroid gland

  • Treatment after the removal of the thyroid for benign or malignant disease

  • After treatment of hyperthyroidism by radioactive iodine ablation

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Who Treats Thyroid Cancer

Depending on the type and stage of your thyroid cancer, you may need more than one type of treatment. Doctors on your cancer treatment team may include:

  • A surgeon: a doctor who uses surgery to treat cancers or other problems
  • An endocrinologist: a doctor who treats diseases in glands that secrete hormones
  • A radiation oncologist: a doctor who uses radiation to treat cancer
  • A medical oncologist: a doctor who uses chemotherapy and other medicines to treat cancer

Many other specialists may be involved in your care as well, including nurse practitioners, nurses, psychologists, social workers, rehabilitation specialists, and other health professionals.

Reasons For Thyroid Surgery

The most common reason for thyroid surgery is the presence of nodules or tumors on the thyroid gland. Most nodules are benign, but some can be cancerous or precancerous.

Even benign nodules can cause problems if they grow large enough to obstruct the throat, or if they stimulate the thyroid to overproduce hormones .

Surgery can correct hyperthyroidism. Hyperthyroidism is frequently the result of an autoimmune disorder called Graves disease.

Graves disease causes the body to misidentify the thyroid gland as a foreign body and send antibodies to attack it. These antibodies inflame the thyroid, causing hormone overproduction.

Another reason for thyroid surgery is the swelling or enlargement of the thyroid gland. This is referred to as a goiter. Like large nodules, goiters can block the throat and interfere with eating, speaking, and breathing.

There are several different types of thyroid surgery. The most common are lobectomy, subtotal thyroidectomy, and total thyroidectomy.

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Should I Exercise If I Have A Thyroid Disease

Regular exercise is an important part of a healthy lifestyle. You do not need to change your exercise routine if you have a thyroid disease. Exercise does not drain your bodys thyroid hormones and it shouldnt hurt you to exercise. It is important to talk to your healthcare provider before you start a new exercise routine to make sure that its a good fit for you.

When Should I See My Healthcare Provider About Thyroiditis

How to get rid of an overactive thyroid gland in 3 easy steps

If youve been diagnosed with thyroiditis, youll need to see your healthcare provider regularly to monitor your symptoms and make sure your treatment is working.

If you develop worse or more concerning symptoms, call your provider as soon as possible.

A note from Cleveland Clinic

While its usually stressful to learn you have a medical condition, the good news is that thyroiditis is highly treatable and it may even be temporary. If you have any questions about thyroiditis or your treatment plan, talk to your healthcare provider. Theyre available to help you.

Last reviewed by a Cleveland Clinic medical professional on 06/07/2022.


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C Effects Of Replacement Therapy With Thyroid Hormone In Severe Cardiac Diseases And Dyslipidemia

The physiological action of thyroid hormone is mediated by its genomic nuclear effects. These effects result from the binding of T3 to specific nuclear TRs.

In the human heart, 2 TR genes are expressed and each gene generates 2 isoforms of receptors . TR transcripts are abundant in the heart, whereas TR2 acts as a negative regulator because it functions by suppressing TR1 transcription . TR1 is widely expressed and has a high expression in cardiac and skeletal muscles. TR1 is predominantly expressed in the brain, liver, and kidney. TR2 expression is limited to the hypothalamus and pituitary .

1. Analogs of thyroid hormone for treatment of obesity and dyslipidemia

a. 3,5,3-Triiodothyroacetic acid.
b. Sobetirome.
c. KB141.

KB141 is another TR agonist that is approximately 15 times more selective for TR than for TR in vitro and is able to induce weight loss and reduce cholesterol and lipoprotein with no effect on heart rate .

d. Eprotirome .

KB2115 – phenoxy)-phenyl)-amino-3-oxopropanoic acid) is a TR-selective ligand that is preferentially taken up by the liver.

2. Thyroid hormone and thyroid hormone analogs for treatment of HF

a. Treatment with thyroid hormone.

Malik et al administered iv l-T4 in 10 consecutive patients with severe systolic HF that had progressed to cardiogenic shock. The authors observed a significant improvement in cardiac index, pulmonary capillary wedge pressure, and mean arterial pressure 24 and 36 hours after l-T4 administration.

Natural Remedies For Hypothyroidism

The standard treatment for hypothyroidism is taking daily thyroid hormone replacement medication. Of course, medications often come with side effects, and forgetting to take a pill might lead to more symptoms.

In some cases, natural remedies may cause fewer side effects and fit into your overall lifestyle better.

The goal of natural remedies or alternative medicine is to fix the root cause of the thyroid problem. Thyroid problems sometimes start as the result of:

Changing your diet and taking an herbal supplement are two ways you can help your thyroid condition. These options may have fewer side effects than taking thyroid medication.

Also, taking an herbal supplement to help address a low or underactive thyroid may be helpful for people who arent responding well to medications.

Consider the following five natural remedies as additions or alternatives to your treatment plan.

, selenium is a trace element that plays a part in thyroid hormone metabolism.

Many foods contain selenium, including:

Hashimotos thyroiditis, an immune system attack on the thyroid, often reduces the bodys selenium supply. Supplementing this trace element has shown to help balance thyroxine, or T4, levels in some people.

Its important to talk with your doctor about how much selenium may be right for you since every person is different.

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Should I Take Thyroid Hormone While I Am Pregnant

Since thyroid hormone is a hormone normally present in your body, it is absolutely safe to take while pregnant. In fact, it is especially important for pregnant women, or women who are planning a pregnancy, to have normal thyroid function for the health of their baby. If you are on thyroid hormone, you will likely need an increased dose of thyroid hormone during pregnancy. As soon as you know you are pregnant you should immediately increase your dose by 20-30% and contact your doctor. An easy way to increase the dose is to take double your usual dose two days a week. You should discuss the timing of thyroid blood tests with your physician, but often thyroid function is checked at least every trimester, and more frequently in the first half of pregnancy.

B Limitations In Peripheral Markers Of Thyroid Hormone Action

Natural Remedies for Hypothyroidism in Women

The evaluation of peripheral parameters of thyroid hormone action could be useful in monitoring l-T4 treatment in CH . A recent study employed Doppler echocardiography to diagnose subclinical CH in patients with hypothalamic-pituitary disease . Unfortunately, evaluation of tissue parameters of thyroid hormone action can be frequently ineffective in CH due to confounding effects of concomitant pituitary deficiencies in somatotrope, gonadal, or adrenal function or the coexistence of cardiac disease.

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A Feedback Regulation Of Thyroid Secretion

Thyroid hormones are produced by the thyroid gland through the iodination of tyrosine residues in the glycoprotein Tg. The anterior pituitary releases TSH in response to TRH, which is secreted by hypothalamus . TSH acts directly on the TSH receptor expressed on the thyroid follicular cell membrane. TSH regulates iodide uptake mediated by the sodium/iodide symporter and stimulates thyroid hormone synthesis and secretion . The thyroid gland secretes both T4 and T3, which exert a negative feedback on TRH and TSH secretion. TSH secretion by the pituitary gland is the result of a complex feedback interaction between central hypothalamic TRH control and thyroidal production of thyroid hormones to the periphery. This negative feedback loop maintains levels of the circulating thyroid hormones and TSH in a physiological inverse relationship that defines the hypothalamic-pituitary-thyroid axis set-point, which is genetically determined and variable among individuals . The set-point for TSH secretion depends on both circulating serum T3 and intracellular pituitary T3. It may be influenced by environmental factors, iodine intake, age, and systemic illness as the organism autoregulates deiodinase activity and the resultant conversion of T4 to T3 .

Who Does Thyroiditis Affect

Thyroiditis can affect anyone, but it more commonly affects people assigned female at birth especially adults.

Hashimotos thyroiditis is four to 10 times more common in people AFAB than in people assigned male at birth . It most often develops in people AFAB between the age of 30 to 50.

Silent or painless thyroiditis is also common in people AFAB and is the next common cause of thyroiditis after Hashimotos thyroiditis.

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Considering Complementary And Alternative Methods

You may hear about alternative or complementary methods that your doctor hasnt mentioned to treat your cancer or relieve symptoms. These methods can include vitamins, herbs, and special diets, or other methods such as acupuncture or massage, to name a few.

Complementary methods refer to treatments that are used along with your regular medical care. Alternative treatments are used instead of a doctors medical treatment. Although some of these methods might be helpful in relieving symptoms or helping you feel better, many have not been proven to work. Some might even be harmful.

Be sure to talk to your cancer care team about any method you are thinking about using. They can help you learn what is known about the method, which can help you make an informed decision.

C Thyroid Hormone Formulations: Pharmacokinetics And Pharmacodynamics

How a thyroid gland can become underactive

Thyroid hormone preparations available for therapy fit into 2 categories: natural hormonal preparations derived from animal thyroid and synthetic preparations.

1. Thyroid extracts

Natural preparations include desiccated thyroid and Tg. Desiccated thyroid products are derived from the thyroid glands of domesticated animals that are used for food by man , and Tg is derived from the thyroid glands of the hog. The content of thyroid hormone and the ratio of T4 to T3 may vary in desiccated thyroid preparations, depending on the brand employed and whether it is of porcine or bovine origin. Desiccated thyroid contains approximately 80% T4 and 20% T3 as well as other iodinated compounds . Absorption studies indicate that the bioavailability of T3 in desiccated thyroid is comparable to that of orally administered synthetic T3.

The most commonly used form of desiccated thyroid, known as Armour Thyroid, is of porcine origin and may be viewed as a mixture of T3 and T4 . Other commercial preparations derived from animal thyroid extracts are Prothyroid, Novothyral, Thyreotom, Thyrolar-3, and Diotroxin.

2. Levothyroxine

3. Different T4 formulations: branded vs generic preparations

4. Liothyronine

5. Preparations containing both l-T3 and l-T4

6. Liquid thyroid hormone preparations

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What Are The Differences Between Thyroid Drugs

Thyroid hormone preparations can be divided into two categories:

  • Natural preparations derived from animal thyroid
  • Synthetic preparations manufactured in a laboratory.

Natural preparations include desiccated thyroid and thyroglobulin.

The most common medication used for supplementation is synthetic thyroxine, also called levothyroxine. This is identical to the T4 hormone. T4 is converted into T3 in the body.

Liothyronine is another thyroid hormone that may be prescribed to people who are unable to properly convert T4 into T3.

Liotrix is a combination of levothyroxine and liothyronine in a 4:1 ratio. Although the ratio remains the same, there are multiple strengths of this medication, so ensure you receive the correct dose.


It is important that levothyroxine is taken on an empty stomach at least 30 to 60 minutes before breakfast to ensure that it is absorbed properly. It should be taken with a big glass of water, and spaced apart by at least four hours from antacids or supplements such as calcium or iron.

Combination Medications With Synthetic T3 And T4 Hormones

Also available on the market are combination medications that contain both synthetic T4 and T3 hormones, but such medications arent usually recommended. For one thing, most patients see their condition improve with synthetic T4 alone because of the ability of the thyroid to convert these hormones to T3 when needed.

In some cases, your doctor may recommend a separate T3 medication called liothyronine in addition to levothyroxine.

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Will Thyroid Hormone Help Me If I Have Hypothyroid Symptoms But Normal Thyroid Hormone Levels

Some people with normal thyroid blood tests have symptoms that are similar to symptoms of hypothyroidism. Several scientific studies have looked at whether T4 therapy would be of benefit to patients with symptoms that overlap with hypothyroid symptoms and normal thyroid function. There has been no proven benefit in taking T4 for improving symptoms if thyroid hormone levels are normal. If thyroid lab values are normal, symptoms are not likely to be due to a thyroid problem and patients should discuss other potential causes or treatment with their physician.

Persistently Elevated Tsh Despite Thyroid Hormone Replacement

8 Powerful Herbal Remedies for Hyperthyroidism

Poor compliance is the most common reason for continued elevation of the TSH level in patients receiving presumably adequate thyroid hormone replacement. Patients who do not regularly take their replacement medication and then try to âcatch upâ just before a physician visit may restore their free T4 levels to normal but continue to have an elevated TSH level.

Very rarely, patients have tissue-level unresponsiveness to thyroid hormone. This condition reflects a mutation in the gene that controls a receptor for T3, rendering it unable to bind with the hormone. The genetic mutation has been identified in only 300 families.22 In these patients, adequate amounts of thyroid hormone are produced but are ineffective. Consequently, the TSH level remains elevated, and the patients continue to have symptoms of hypothyroidism. These patients should be referred to an endocrinologist for further evaluation and management.

Increase replacement requirements

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